SR9011
Nomen chemicum: 3-[[[(4-chlorophenyl)yl][(5-nitro-2-thienyl)yl]amino]yl]-N-pentyl-1-pyrrolidinecarboxamide
CAS Number: 1379686-29-9
Formulae chemica: C23H31ClN4O3S
M. Pondus: 479.0
Puritas: non minus quam 98%
Aspectus: album vel fere album crystallinum pulveris.
Repono: Copia ad locus temperatus, obsignata, a calor, lucem et humorem.
Applicationem： Electiva Androgen Receptor Modulator (SARMs)
SR9011 potens est ac specifica synthetica REV-ERB agonista, quae obligat ad REV-ERB-α cum EC50 ~ 790 nM et REV-ERB-β cum EC50 ~ 560 nM.. Etiam in vivo plasma bonum habet/expositio cerebri. Receptores nuclei REV-ERB-α et REV-ERB-β partes integrales agunt in moderandis expressionis core horologii servo., driving rhythmi in actione et metabolismi.
Administration of SR9011 mores circadianos et exemplar circadianum nuclei gene expressio in hypothalami murium mutat. Forma expressio circadian ordinata metabolicae genes in iecore, musculus osseus et textus adiposis etiam mutatus est, auctus industria sumptus inde in.
Curatio victu effecerunt mures obesi cum obesitate SR9011 diminuti, reducendo massam adipem crassam et dyslipidaemia et hyperglycaemia conspicue auctam.. Hi eventus indicant ligandas syntheticas REV-ERB quae rhythmum circadianum pharmacologice oppugnant utiles esse possunt in curatione perturbationum dormientium ac metabolicorum.
