Sildenafil Mesylate CAS:131543-23-2

Användande: Farmaceutiska råvaror, afrodisiakum Det är medicin behandling råvara, indicerat för behandling av erektil dysfunktion.

Sildenafilmesylat, samma som Sildenafil är en hämmare av typen 5 -cGMP fosfodiesteras avslappnande och utjämnande muskelceller i corpus cavernosum vilket leder till erektion av penis. Denna avslappning kan förmedlas av kväveoxid via cykliskt guanosinmonofosfat., hormon. As a cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective inhibitor, penile smooth muscle relaxation allows rapid erection. Sildenafil is cheap, is the development and production of low-cost classes available kidney yang-like the perfect material for medicine and health products.

I 16 separate 4-24 week trials of men (over 18 år gammal) who suffered from impotence for longer than 6 månader, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfi* treatment compared to the placebo group.

Erections were improved in 72% of group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.