Tadalafil cas:171596-29-5

Användande: ett oralt läkemedel som används för att behandla impotens (oförmågan att uppnå eller upprätthålla en penilerektion) och godartad prostatahyperplasi (BPH)

Tadalafil (Tadalifilcitrat), en fosfodiesteras -typ 5 inhibitor, används för att behandla erektil dysfunktion (Ed) och minskad libido hos män. Tadalafil works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function. Tadalafil is much longer lasting.

Tadalafil is used for Erectile dysfunction and pulmonary hypertension, the rapid absorption after oral administration, 2 hours to reach maximum observed plasma concentrations of average time after administration of (Cmax). Influence of absorption rate and degree is not affected by food tadalafil, so it can be with or without with clothes and food.

Tadalafil is an oral drug for the treatment of ED, används vid behandling av erektil dysfunktion och för tidig utlösning, erektil funktionsnedsättning och för tidig utlösning har mycket betydande förbättringar. Det finns över 1500 dokument för att bevisa orsakas av olika orsaker impotens för tidig utlösning, visste att framgångsfrekvensen är över 80%, och visa dess pålitliga botande effekt, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.

Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain.In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.

Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half-life and reduce serum levels, and hence efficacy, of the drug.

Tadalafil has been used in approximately 15,000 men participating in clinical trials, and over eight million men worldwide(primarily in the post-approval/post-marketing setting). The most common side effects when using tadalafil are headache, stomach discomfort or pain, indigestion, burping, acid reflux, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to cause vasodilation (cause blood vessels to widen), and usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.