FMG CAS:12020-86-9

FMG (facteur de croissance mécano) est utilisé par les bodybuilders et les athlètes depuis quelques années déjà. Après un exercice de résistance, L'IGF-1 est libéré dans le muscle. Spécifiquement, à ce moment, immédiatement après l'utilisation mécanique d'un muscle, le gène IGF-I est épissé vers le MGF qui initie l'hypertrophie et la réparation des lésions musculaires locales. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. It differs from “regular” IGF-1 mainly due to it’s C-Terminal sequence.

In a rodent study, a single intramuscular injection into muscle resulted in a 25% increase in mean muscle fibre cross section area within three weeks.Using a similar protocol, liver-derived IGF-1 took four months to produce a 15% augmenter.

It would also appear that with regards to age, the young have a better ability to respond to MGF, and that the elderly experience a decreased response to MGF which results in a decreased ability to stimulate the growth of new muscle tissue.