MGF CAS:12020-86-9

MGF (Mechano-Wachstumsfaktor) wird bereits seit einigen Jahren von Bodybuildern und Sportlern verwendet. Nach Widerstandstraining, IGF-1 wird im Muskel freigesetzt. Speziell, zu diesem Zeitpunkt, unmittelbar nach der mechanischen Beanspruchung eines Muskels, Das IGF-I-Gen wird in Richtung MGF gespleißt, was die Hypertrophie und die Reparatur lokaler Muskelschäden initiiert. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. It differs from “regular” IGF-1 mainly due to it’s C-Terminal sequence.

In a rodent study, a single intramuscular injection into muscle resulted in a 25% increase in mean muscle fibre cross section area within three weeks.Using a similar protocol, liver-derived IGF-1 took four months to produce a 15% Zunahme.

It would also appear that with regards to age, the young have a better ability to respond to MGF, and that the elderly experience a decreased response to MGF which results in a decreased ability to stimulate the growth of new muscle tissue.