MGF
English synonym: Mechano-Growth Factor
شماره CAS: 12020-86-9
فرمول مولکولی: FKLiMgO5Si2+
وزن مولکولی: 225.51
شماره EINECS: 200-001-8
MGF (عامل رشد مکانیکی) چند سالی است که توسط بدنسازان و ورزشکاران استفاده می شود. بعد از تمرین مقاومتی, IGF-1 درون عضله آزاد می شود. به طور خاص, در این زمان, بلافاصله پس از استفاده مکانیکی از یک عضله, ژن IGF-I به سمت MGF متصل می شود که باعث هیپرتروفی و ترمیم آسیب عضلانی موضعی می شود.. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. It differs from “regular” IGF-1 mainly due to it’s C-Terminal sequence.
In a rodent study, a single intramuscular injection into muscle resulted in a 25% increase in mean muscle fibre cross section area within three weeks.Using a similar protocol, liver-derived IGF-1 took four months to produce a 15% increase.
It would also appear that with regards to age, the young have a better ability to respond to MGF, and that the elderly experience a decreased response to MGF which results in a decreased ability to stimulate the growth of new muscle tissue.
