4-Androstenediol CAS:1156-92-9

4-Androstenediol, also known as androst-4-ene-3β,17β-diol, est androstenediol quod convertitur ad testosterone. Conversio rate est de 15.76%, prope triplum quod IV-androstenedione, ex alia enzymatic via utendo. Est etiam aliqua conversio in estrogen, quoniam testosterone metabolicae praecursor estrogens.

4-Androstenediol propius ad testosterone constitutione quam V-androstenediol, et effectus habet androgenic, acting as a weak partial agonist of the androgen receptor.However, due to its lower intrinsic activity in comparison, in the presence of full agonists like testosterone or dihydrotestosterone (DHT), 4-androstenediol has antagonistic actions, behaving more like an antiandrogen.

4-Androstenediol is very weakly estrogenic. It has approximately 0.5% et 0.6% of the affinity of estradiol at the ERα and ERβ, respective.