Deslorelin asetat enjekte edilebilir bir gonadotropin salgılayan hormon süper agonistidir. (GnRH agonisti) LHRH agonisti olarak da bilinir. Seks hormonlarının üretimini durdurur (testosteron ve östrojen).
Deslorelin Asetat Peptech tarafından Ovuplant markasıyla pazarlanmaktadır.. It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit luteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.
Başvuru:
Deslorelin was successfully trialed in the US and was approved for veterinary use under certain circumstances. In Europe, it was approved for use in equine assisted reproduction.
It is also being trialed in humans to study its efficacy in treatment of breast cancer in women,and in treating precocious puberty and congenital adrenal hyperplasia in male and female children.