Oxytocin CAS:50-56-6

Användande : För induktion av förlossning, oxytocin efter förlossningen, och abort på grund av uterin atoni eller retraktion orsakad av den dåliga livmoderns blödning; förstå placentafunktionsreserven (oxytocinutmaningstest); näsdroppar kan främja mjölkutstötning.

Oxytocin (Oxt) är ett neurohypofysiskt hormon från däggdjur. Produceras av hypotalamus och lagras och utsöndras av den bakre hypofysen, oxytocin acts primarily as a neuromodulator in the brain.

Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth; its name, meaning “swift childbirth”, comes from Greek, oksys “swift” och , tokos “birth.” It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, och, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.

Ansökan:

Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 och 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine, salbutamol, and terbutaline).