PT141 CAS:189691-06-3

PT-141 Description

PT-141 (برملانوتید) یک آنالوگ پپتید مصنوعی بسیار قوی از α-MSH است که ممکن است از طریق تحریک گیرنده های ملانوکورتین، اثرات آفرودیزیاکی ایجاد کند.. PT-141 (برملانوتید) متشکل از هفت اسید آمینه و حلقوی است, نوع لاکتام کوتاه شده هورمون محرک آلفا ملانوسیت (α-MSH), یک پپتید چند منظوره که مجموعه وسیعی از عملکردهای فیزیولوژیکی را تنظیم می کند. در مطالعات, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

PT-141 Usage

PT-141, bremelanotide is experimental and is used for the purpose of sexual arousal. It is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger. An example of findings among male rats is displayed below in an abstract from this Palatin study:

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder).

برملانوتید, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.