CAS : 139755-83-2
Kimyasal Formül: C22H19N3O4
Moleküler ağırlık: 389.4
Content: 99.5% Sildenafil sitrat, Viagra
Solubility: Slightly soluble in water, methanol; very slightly soluble in ethanol, chloroform
Dış görünüş: Beyaz kristal toz
Depolamak: shading, sınırlı koruma.
Kullanım: Viagra (Sildenafil sitrat) Erektil disfonksiyon tedavisinde kullanılan bir ilaçtır (iktidarsızlık) erkeklerde ve pulmoner arteriyel hipertansiyonda (PAH).
Sildenafil sitrat, Viagra olarak satılıyor, Sildenafil ED tedavisi için oral bir ilaçtır, Erektil disfonksiyon ve erken boşalma tedavisinde kullanılır, Erektil fonksiyon bozukluğu ve erken boşalmada çok önemli iyileşmeler var. bitti 1500 İktidarsızlık, erken boşalma, farklı nedenlerden kaynaklandığını kanıtlayan belgeler,başarı oranının yukarıda olduğunu biliyordum 80%, ve güvenilir iyileştirici etkisini gösterin, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
