کلومیفن سیترات یک داروی هورمونی است که بیشتر با نام تجاری Clomid شناخته می شود. این دارو اغلب برای درمان ناباروری ناشی از تخمک گذاری نامنظم یا عدم تخمک گذاری استفاده می شود. می تواند کاربردهای دیگری نیز داشته باشد, مانند تولید تخمک گذاری بیشتر برای جمع آوری تخمک, برای تنظیم مختصر چرخه تخمک گذاری, و گهگاه برای افزایش سطح اسپرم در مردان. The drug is typically used for a short time only, and especially in cases where achieving pregnancy is the goal, use doesn’t exceed about six months. It’s generally thought that failure of clomiphene to achieve pregnancy by the six-month mark suggests the drug will not ever be effective.
Clomiphene citrate is used to treat infertility in women. It works by stimulating an increase in the amount of hormones that support the growth and release of a mature egg (تخمک گذاری). This medication is not recommended for women whose ovaries no longer make eggs properly (primary pituitary or ovarian failure).
Clomifene citrate blocks the effect of the hormone oestrogen in your body. This blocking effect tricks your body into bumping up levels of two other hormones that are essential forovulationThese two other hormones are:
Follicle-stimulating hormone (FSH)
And luteinising hormone (LH)
FSH causes the eggs in your ovaries to ripen, ready for release. LH triggers the release of one or more mature eggs from the ovaries. The egg or eggs then move down into one of your fallopian tubes.